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1

Metabolic control analysis in drug discovery and disease

Cascante, Marta, Boros, Laszlo G., Comin-Anduix, Begoña, de Atauri, Pedro, Centelles, Josep J., Lee, Paul W.-N.

Journal:

Nature Biotechnology

Année:

2002

Langue:

english

Fichier:

PDF, 84 KB

english, 2002

2

Multicriteria optimization of biochemical systems by linear programming: Application to production of ethanol by Saccharomyces cerevisiae

Julio Vera, Pedro De Atauri, Marta Cascante, Néstor V. Torres

Journal:

Biotechnology and Bioengineering

Année:

2003

Langue:

english

Fichier:

PDF, 185 KB

english, 2003

3

Is the regulation of galactose 1-phosphate tuned against gene expression noise?

de ATAURI, Pedro, ORRELL, David, RAMSEY, Stephen, BOLOURI, Hamid

Journal:

Biochemical Journal

Année:

2005

Langue:

english

Fichier:

PDF, 322 KB

english, 2005

4

Analysis and prediction of the effect of uncertain boundary values in modeling a metabolic pathway

Pedro de Atauri, Albert Sorribas, Marta Cascante

Journal:

Biotechnology and Bioengineering

Année:

2000

Langue:

english

Fichier:

PDF, 361 KB

english, 2000

5

In silico strategy to rationally engineer metabolite production: A case study for threonine in Escherichia coli

Juan-Carlos Rodríguez-Prados, Pedro de Atauri, Jérôme Maury, Fernando Ortega, Jean-Charles Portais, Christophe Chassagnole, Luis Acerenza, Nic D. Lindley, Marta Cascante

Journal:

Biotechnology and Bioengineering

Année:

2009

Langue:

english

Fichier:

PDF, 375 KB

english, 2009

6

Dependence of Control Coefficient Distribution on the Boundaries of a Metabolic System: A Generalized Analysis of the Effects of Additional Input and Output reactions to a Linear Pathway

PEDRO DE ATAURI, DAVID A. FELL, CHRISTOPHE CHASSAGNOLE, DOLORS MAGRET, JEAN PIERRE MAZAT, MARTA CASCANTE

Journal:

Journal of Theoretical Biology

Année:

2002

Langue:

english

Fichier:

PDF, 307 KB

english, 2002

7

Feedback control of stochastic noise in the yeast galactose utilization pathway

David Orrell, Stephen Ramsey, Marcello Marelli, Jennifer J. Smith, Timothy W. Petersen, Pedro de Atauri, John D. Aitchison, Hamid Bolouri

Journal:

Physica D: Nonlinear Phenomena

Année:

2006

Langue:

english

Fichier:

PDF, 2.09 MB

english, 2006

8

Effects of feedback inhibition on transit time in a linear pathway of Michaelis–Menten-type reactions

Naoto Sakamoto, Pedro de Atauri, Marta Cascante

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 232 KB

english, 1998

9

Mathematical modelling of the urea cycle : A numerical investigation into substrate channelling

Anthony D. Maher, Philip W. Kuchel, Fernando Ortega, Pedro de Atauri, Josep Centelles, Marta Cascante

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 222 KB

english, 2003

10

Advantages and disadvantages of aggregating fluxes into synthetic and degradative fluxes when modelling metabolic pathways

Pedro de Atauri, Raul Curto, Joaquim Puigjaner, Athel Cornish-Bowden, Marta Cascante

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 566 KB

english, 1999

11

Metabolic homeostasis in the human erythrocyte: In silico analysis

Pedro de Atauri, María José Ramírez, Philip W. Kuchel, José Carreras, Marta Cascante

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 161 KB

english, 2006

12

Dual feedback loops in the GAL regulon suppress cellular heterogeneity in yeast

Ramsey, Stephen A, Smith, Jennifer J, Orrell, David, Marelli, Marcello, Petersen, Timothy W, de Atauri, Pedro, Bolouri, Hamid, Aitchison, John D

Journal:

Nature Genetics

Année:

2006

Langue:

english

Fichier:

PDF, 195 KB

english, 2006

13

Metabolic Control Analysis Aimed at the Ribose Synthesis Pathways of Tumor Cells: A New Strategy for Antitumor Drug Development

Joan Boren, Antonio Ramos Montoya, Pedro de Atauri, Begoña Comin-Anduix, Antonio Cortes, Josep J. Centelles, Wilma M. Frederiks, Cornelis J.F. Van Noorden, Marta Cascante

Journal:

Molecular Biology Reports

Année:

2002

Fichier:

PDF, 2.35 MB

2002

14

Carbon metabolism and the sign of control coefficients in metabolic adaptations underlying K-ras transformation

Pedro de Atauri, Adrian Benito, Pedro Vizán, Miriam Zanuy, Ramón Mangues, Silvia Marín, Marta Cascante

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Année:

2011

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2011

15

Characterization of the first described mutation of human red blood cell phosphoglycerate mutase

Pedro de Atauri, Ada Repiso, Baldomero Oliva, Joan Lluis Vives-Corrons, Fernando Climent, José Carreras

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Année:

2005

Langue:

english

Fichier:

PDF, 307 KB

english, 2005

16

Enzymatic and metabolic characterization of the phosphoglycerate kinase deficiency associated with chronic hemolytic anemia caused by the PGK-Barcelona mutation

María José Ramírez-Bajo, Ada Repiso, Pablo Pérez de la Ossa, Elisenda Bañón-Maneus, Pedro de Atauri, Fernando Climent, Joan-Lluís Vives Corrons, Marta Cascante, José Carreras

Journal:

Blood Cells, Molecules, and Diseases

Année:

2011

Langue:

english

Fichier:

PDF, 367 KB

english, 2011

17

Characterization of the transit and transition times for a pathway unit of Michaelis–Menten mechanism

Naoto Sakamoto, Pedro de Atauri, Marta Cascante

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Année:

2003

Langue:

english

Fichier:

PDF, 185 KB

english, 2003

18

Dynamic simulation of pollutant effects on the threonine pathway in Escherichia coli

Christophe Chassagnole, Éric Quentin, David A. Fell, Pedro de Atauri, Jean-Pierre Mazat

Journal:

Comptes Rendus Biologies

Année:

2003

Fichier:

PDF, 314 KB

2003

19

Surgical lung cancer

López-Encuentra, Angel, Pozo-Rodrı́guez, Francisco, Martı́n-Escribano, Pedro, Martı́n de Nicolás, José Luis, Dı́az de Atauri, Marı́a Josefa, Palomera, Jesús, Marrón, Carmen

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 139 KB

english, 2004

20

Sampling with poling-based flux balance analysis: optimal versus sub-optimal flux space analysis of Actinobacillus succinogenes

Binns, Michael, de Atauri, Pedro, Vlysidis, Anestis, Cascante, Marta, Theodoropoulos, Constantinos

Journal:

BMC Bioinformatics

Année:

2015

Langue:

english

Fichier:

PDF, 1.24 MB

english, 2015

21

A 73-Year-Old Man with Interstitial Lung Disease Due to Dronedarone

Hernández Voth, Ana R., Catalán, Javier Sayas, Benavides Mañas, Pedro D., Ávila Martínez, Régulo J., Peñalver Paolini, Carlos L., Díaz de Atauri Rodríguez, María J.

Journal:

American Journal of Respiratory and Critical Care Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 301 KB

english, 2012

22

ChainRank, a chain prioritisation method for contextualisation of biological networks

Tényi, Ákos, de Atauri, Pedro, Gomez-Cabrero, David, Cano, Isaac, Clarke, Kim, Falciani, Francesco, Cascante, Marta, Roca, Josep, Maier, Dieter

Journal:

BMC Bioinformatics

Année:

2016

Langue:

english

Fichier:

PDF, 2.46 MB

english, 2016

23

Sleep-Related Breathing Disorders and Lung Transplantation

Hernandez Voth, Ana R., Benavides Mañas, Pedro D., De Pablo Gafas, Alicia, de Atauri Rodríguez, María J. Díaz

Journal:

Transplantation Journal

Année:

2015

Langue:

english

Fichier:

PDF, 209 KB

english, 2015

24

Occurrence of paradoxical or sustained control by an enzyme when overexpressed: necessary conditions and experimental evidence with regard to hepatic glucokinase

DE ATAURI, Pedro, ACERENZA, Luis, KHOLODENKO, Boris N., DE LA IGLESIA, Núria, GUINOVART, Joan J., AGIUS, Loranne, CASCANTE, Marta

Journal:

Biochemical Journal

Année:

2001

Langue:

english

Fichier:

PDF, 165 KB

english, 2001

25

Metabolic network adaptations in cancer as targets for novel therapies: Figure 1

Cascante, Marta, Benito, Adrian, Zanuy, Miriam, Vizán, Pedro, Marín, Silvia, de Atauri, Pedro

Journal:

Biochemical Society Transactions

Année:

2010

Langue:

english

Fichier:

PDF, 211 KB

english, 2010

26

Combined Analysis of NMR and MS Spectra (CANMS)

Chong, Mei, Jayaraman, Anusha, Marin, Silvia, Selivanov, Vitaly, de Atauri Carulla, Pedro R., Tennant, Daniel A., Cascante, Marta, Günther, Ulrich L., Ludwig, Christian

Journal:

Angewandte Chemie International Edition

Année:

2017

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2017

27

Combined Analysis of NMR and MS Spectra (CANMS)

Chong, Mei, Jayaraman, Anusha, Marin, Silvia, Selivanov, Vitaly, de Atauri Carulla, Pedro R., Tennant, Daniel A., Cascante, Marta, Günther, Ulrich L., Ludwig, Christian

Journal:

Angewandte Chemie

Année:

2017

Langue:

english

Fichier:

PDF, 1.10 MB

english, 2017

28

Workforce preparation: the Biohealth computing model for Master and PhD students

Marta Cascante,Pedro de Atauri,David Gomez-Cabrero…

Journal:

Journal of Translational Medicine

Année:

2014

Langue:

english

Fichier:

PDF, 341 KB

english, 2014

29

De novo MYC addiction as an adaptive response of cancer cells to CDK4/6 inhibition

Tarrado‐Castellarnau, Míriam, de Atauri, Pedro, Tarragó‐Celada, Josep, Perarnau, Jordi, Yuneva, Mariia, Thomson, Timothy M, Cascante, Marta

Journal:

Molecular Systems Biology

Année:

2017

Langue:

english

Fichier:

PDF, 3.18 MB

english, 2017

30

In-silico gene essentiality analysis of polyamine biosynthesis reveals APRT as a potential target in cancer

Pey, Jon, San José-Eneriz, Edurne, Ochoa, María Carmen, Apaolaza, Iñigo, de Atauri, Pedro, Rubio, Angel, Cendoya, Xabier, Miranda, Estíbaliz, Garate, Leire, Cascante, Marta, Carracedo, Arkaitz, Agirre

Journal:

Scientific Reports

Année:

2017

Langue:

english

Fichier:

PDF, 1.22 MB

english, 2017

31

From correlation to causation: analysis of metabolomics data using systems biology approaches

Rosato, Antonio, Tenori, Leonardo, Cascante, Marta, De Atauri Carulla, Pedro Ramon, Martins dos Santos, Vitor A. P., Saccenti, Edoardo

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 2.02 MB

english, 2018

32

Persistence of Respiratory Abnormalities Four Years After the Onset of Toxic Oil Syndrome

Escribano, Pedro Martín, Atauri, Maria Josefa Díaz de, Gómez Sánchez, Miguel A.

Journal:

Année:

1991

Langue:

english

Fichier:

PDF, 964 KB

english, 1991

33

Network modules uncover mechanisms of skeletal muscle dysfunction in COPD patients

Tényi, Ákos, Cano, Isaac, Marabita, Francesco, Kiani, Narsis, Kalko, Susana G., Barreiro, Esther, de Atauri, Pedro, Cascante, Marta, Gomez-Cabrero, David, Roca, Josep

Journal:

Journal of Translational Medicine

Année:

2018

Langue:

english

Fichier:

PDF, 3.04 MB

english, 2018

34

Strategies for structuring interdisciplinary education in Systems Biology: an European perspective

Cvijovic, Marija, Höfer, Thomas, Aćimović, Jure, Alberghina, Lilia, Almaas, Eivind, Besozzi, Daniela, Blomberg, Anders, Bretschneider, Till, Cascante, Marta, Collin, Olivier, de Atauri, Pedro, Depner,

Journal:

npj Systems Biology and Applications

Année:

2016

Langue:

english

Fichier:

PDF, 364 KB

english, 2016

35

HepatoDyn: A Dynamic Model of Hepatocyte Metabolism That Integrates 13C Isotopomer Data

Foguet, Carles, Marin, Silvia, Selivanov, Vitaly A., Fanchon, Eric, Lee, Wai-Nang Paul, Guinovart, Joan J., de Atauri, Pedro, Cascante, Marta, Lewis, Nathan E

Journal:

PLoS Computational Biology

Année:

2016

Langue:

english

Fichier:

PDF, 2.55 MB

english, 2016

36

Effects of Cadmium and Mercury on the Upper Part of Skeletal Muscle Glycolysis in Mice

Ramírez-Bajo, Maria José, de Atauri, Pedro, Ortega, Fernando, Westerhoff, Hans V., Gelpí, Josep Lluis, Centelles, Josep J., Cascante, Marta, Rodrigues-Lima, Fernando

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 837 KB

english, 2014

37

Untargeted metabolomics reveals distinct metabolic reprogramming in endothelial cells co-cultured with CSC and non-CSC prostate cancer cell subpopulations

Jayaraman, Anusha, Kumar, Praveen, Marin, Silvia, de Atauri, Pedro, Mateo, Francesca, M. Thomson, Timothy, J. Centelles, Josep, F. Graham, Stewart, Cascante, Marta, Nie, Daotai

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 3.31 MB

english, 2018

38

PhenoMeNal: Processing and analysis of Metabolomics data in the Cloud

Peters, Kristian, Bradbury, James, Bergmann, Sven, Capuccini, Marco, Cascante, Marta, de Atauri, Pedro, Ebbels, Timothy M D, Foguet, Carles, Glen, Robert, Gonzalez-Beltran, Alejandra, Günther, Ulrich

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 1.38 MB

english, 2018

39

Tracing metabolic fluxes using mass spectrometry: stable isotope-resolved metabolomics in health and disease

Balcells, Cristina, Foguet, Carles, Tarragó-Celada, Josep, de Atauri, Pedro, Marin, Silvia, Cascante, Marta

Journal:

TrAC Trends in Analytical Chemistry

Année:

2019

Langue:

english

Fichier:

PDF, 2.61 MB

english, 2019

40

Metabolomics in Systems Medicine: an overview of methods and applications

Karakitsou, Effrosyni, Foguet, Carles, de Atauri, Pedro, Kultima, Kim, Khoonsari, Payam Emami, Martins dos Santos, Vitor A.P., Saccenti, Edoardo, Rosato, Antonio, Cascante, Marta

Journal:

Current Opinion in Systems Biology

Année:

2019

Fichier:

PDF, 2.28 MB

2019

41

Oncogenic regulation of tumor metabolic reprogramming

Tarrado-Castellarnau, Míriam, de Atauri, Pedro, Cascante, Marta

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 3.10 MB

english, 2016

42

p13CMFA: Parsimonious 13C metabolic flux analysis

Foguet, Carles, Jayaraman, Anusha, Marin, Silvia, Selivanov, Vitaly A., Moreno, Pablo, Messeguer, Ramon, de Atauri, Pedro, Cascante, Marta, Hatzimanikatis, Vassily

Journal:

PLoS Computational Biology

Année:

2019

Langue:

english

Fichier:

PDF, 2.24 MB

english, 2019

43

p13CMFA: Parsimonious 13C metabolic flux analysis

Foguet, Carles, Jayaraman, Anusha, Marin, Silvia, Selivanov, Vitaly A., Moreno, Pablo, Messeguer, Ramon, de Atauri, Pedro, Cascante, Marta, Hatzimanikatis, Vassily

Journal:

PLoS Computational Biology

Année:

2019

Fichier:

PDF, 2.24 MB

2019

44

[American Thoracic Society American Thoracic Society 2012 International Conference, May 18-23, 2012 â¢ San Francisco, California - ()] C72. SLEEP AND SLEEP DISORDERED BREATHING IN OTHER MEDICAL DISORDERS - Evolution Of Sleep Architecture In Lung Transplant Patients During The First Year After Lung Transplant

Benavides, Pedro, Hernandez, Ana, Jodra, Soraya, Rebolledo, Ximena, De Pablos, Alicia, Diaz De Atauri, Maria Josefa

Année:

2012

Fichier:

PDF, 20 KB

2012